Programme
In response to the epidemic, this year’s symposium will be held in a format that combines online (via ZOOM) and in-person elements, in order to allow participants from around the world to participate in the event.
Participants who are unable to attend the symposium in person can join the meeting on ZOOM. ZOOM ID and password will be provided after registration.
| 13th October 2022 (Thu) Venue: N2 – University Hall PM |
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| 15:00-18:00 | Poster Session Selection by the Poster Review Committee |
| 14th October 2022 (Fri) Venue: N2 – University Hall Day 1 – AM |
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| 08:30-09:00 | Registration/ Guest Reception |
| Opening Ceremony of the 8th Macau Symposium on Biomedical Sciences | |
| 09:00-09:20 |
Welcome Remarks delivered by Prof. Yonghua SONG
Rector of the University of Macau
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Programme Introduction delivered by Prof. Chuxia DENG
Dean of the Faculty of Health Sciences of the University of Macau
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Group Photo
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| Plenary Session | |
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Session Chair(s)
 Chuxia DENG Dean and Chair Professor, Faculty of Health Sciences, University of Macau |
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09:20-10:00 |
 Xiaodong WANG (Keynote Speaker) National Institute of Biological Sciences, Beijing Talk title: Cell Death Pathways Control Organ Specific Aging of Reproductive Systems |
10:00-10:30 |
 Alex K. SHALEK Massachusetts Institute of Technology, USA Talk title: Does Cell State Matter in Cancer |
| 10:30-11:00 | Intermission and Poster Session |
11:00-11:30 |
 Weiping ZOU University of Michigan, USA Talk title: Metabolic Mechanisms in Cancer Immunotherapy |
11:30-12:00 |
 Xiang-Dong FU University of California, San Diego, USA Talk title: Leveraging the REST-PTB Axis to Develop a Therapeutic Strategy for Brain Repair |
12:00-12:30 |
 Wanjin HONG Institute of Molecular and Cell Biology, Singapore Talk title: The Hippo Pathway: Players, Regulators and Cancer Targeting |
| 12:30-13:30 | Lunch Venue: N1 – Multi-function Hall |
| 13:30-14:30 | Poster Session Venue: N2 – University Hall |
| 14th October 2022 (Fri) Venue: N2 – University Hall Day 1 – PM |
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| Session I – Stem Cell Immunogenicity, Tumor Metabolism and Viral Vaccines | |
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Session Chair(s)
 Ren-He XU Distinguished Professor, Faculty of Health Sciences, University of Macau  Guokai CHEN Professor, Faculty of Health Sciences, University of Macau |
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14:30-14:48 |
 Tao TAN Kunming University of Science & Technology Talk title: Ex Utero Monkey Embryogenesis |
14:48-15:06 |
 Tao XU Center for Bio-intelligent Manufacturing and Living Matter Bioprinting, Research Institute of Tsinghua University in Shenzhen Talk title: 3D Bioprinting for Precision and Regenerative Medicine |
15:06-15:24 |
 Ke ZHAO Southern Medical University Talk title: Clinical Application of Mesenchymal Stromal Cells in HSCT |
15:24-15:42 |
 Tiffany HORNG ShanghaiTech University Talk title: Glucose Metabolism Regulates Macrophage Induction and Suppression of Inflammatory Responses |
15:42-16:00 |
 Peixiang LAN Tongji Medical College, Huazhong University of Science & Technology Talk title: LRP11 Promotes Stem-like T Cells via MAPK13-mediated TCF1 Phosphorylation Enhancing Anti-PD1 Immunotherapy |
| 16:00-16:30 | Intermission and Poster Session |
| Session II – Autophagy and lysosome Biology in Health and Disease | |
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Session Chair(s)
 Han-Ming SHEN Chair Professor, Faculty of Health Sciences, University of Macau Co-chair(s)
 Jiahong LU Associate Professor, Institute of Chinese Medical Sciences |
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16:30-16:52 |
 Bin LU University of South China Talk title: Mitochondrial LONP1 Protease and Cancer |
16:52-17:15 |
 Wei LIU Zhejiang University Talk title: ORP8 Acts as a Lipophagy Receptor to Mediate Lipid Droplet Turnover |
17:15-17:37 |
 Zhiyin SONG Wuhan University Talk title: Mitochondiral Quality Control Under Stress |
17:37-18:00 |
 Xingguo LIU Guangzhou Institutes of Biomedicine and Health, CAS Talk title: Mitochondrial Remodeling for Stem Cell Fate Determination |
| 18:30-21:00 | Gala Dinner Venue: 百老匯好彩海鮮火鍋飯店 *For speakers, academic staff and invited guests |
| 15th October 2022 (Sat) Venue: N2 – University Hall Day 2 – AM |
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| Session III – Neuroscience, Aging and Degenerative Diseases | |
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Session Chair(s)
 Wenhua ZHENG Professor, Faculty of Health Sciences, University of Macau Co-chair(s)
 Hong-Shuo SUN University of Toronto |
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09:00-09:18 |
 Zhong-Ping FENG University of Toronto Talk title: Calcium-dependent Mechanisms Underlying Learning and Memory |
09:18-09:36 |
Hong-Shuo SUN University of Toronto Talk title: Lon Channels in Drug Development for Neuroprotection |
09:36-09:54 |
 Jian-Gang SHEN The University of Hong Kong Talk title: Oxidative Redox Signaling as Therapeutic Targets for Reducing Thrombolytic Hemorrhagic Transformation in Ischemic Stroke: Application for Chinese Medicine |
09:54-10:12 |
 Ying PENG Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Talk title: Pathological Features and Clinical Trials interfere with Encephalopathia Alcoholica |
10:12-10:30 |
 Jun LIU The Second Affiliated Hospital, Guangzhou Medical University Talk title: Neuroprotective Therapeutic Strategies for Alzheimer’s disease |
| 10:30-11:00 | Intermission and Poster Session |
| Session IV – Immune Responses and Its Regulation | |
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Session Chair(s)
 Xin CHEN Distinguished Professor, Institute of Chinese Medical Sciences |
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11:00-11:15 |
 Yiwei CHU Fudan University Talk title: Regulatory B lymphocytes in Diseases |
11:15-11:30 |
 Xiaoyu HU Tsinghua University Talk title: Targeting KDM5A Induction and TLR Activation to Improve Response to Immune Checkpoint Blockade |
11:30-11:45 |
 Qingqing WANG Zhejiang University Talk title: Suppressive Myeloid Cells Shape the Tumor Immune Microenvironment |
11:45-12:00 |
 Hanjie LI Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Talk title: Spatial-temporal Dynamics of Macrophage Specification during Human Prenatal Development |
12:00-12:15 |
 Xiaoren ZHANG Guangzhou Medical University Talk title: Histone Methylation in Immunity and Diseases |
12:15-12:30 |
 Yanfeng GAO School of Pharmaceutical Sciences (Shenzhen), Sun Yat-Sen University Talk title: Discovery of Peptide Inhibitors Targeting Novel Immune Checkpoints for Cancer Immunotherapy |
| 12:30-14:00 | Lunch Venue: N1 – Multi-function Hall |
| 14:00-14:30 | Presentations by the 2-3 winners of Best Poster Award Venue: N2 – University Hall |
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Session Chair(s)
 Leo LEE Associate Professor, Faculty of Health Sciences, University of Macau  Tzu-ming LIU Associate Professor, Faculty of Health Sciences, University of Macau |
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| 15th October 2022 (Sat) Venue: N2 – University Hall Day 2 – PM |
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| Session V – Glycoscience and Herbal Medicine | |
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Session Chair(s)
 Shaoping LI Distinguished Professor, Institute of Chinese Medical Sciences |
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14:30-14:48 |
 Peixue LING Shandong University Talk title: Development and Application of Biological Polysaccharides |
14:48-15:06 |
 Kan DING Zhongshan Institute for Drug Discovery, SIMM, Chinese Academy of Science Talk title: Bioactive Polysaccharide against SARS-CoV-2 Virus via Targeting 3CLpro and PLpro and RdRp from Herbal Medicine |
15:06-15:24 |
 Fengshan WANG Shandong University Talk title: Curdlan Sulfate/O-linked Quaternized Chitosan Nanoparticles: Potential Adjuvants to Improve the Immunogenicity of Exogenous Antigens via Intranasal Vaccinization |
15:24-15:42 |
 Fei LIU Shandong Academy of Pharmaceutical Sciences Talk title: Study on the Improvement of Preparation Technology and Application of Pullulan |
15:42-16:00 |
 Chunming WANG University of Macau Talk title: Exploring ‘new’ Activities of Glycans for Tissue Repair – From Polysaccharide Scaffolds to Oligosaccharide Molecules |
| 16:00-16:30 | Intermission and Poster Session |
| Session VI – Development of Smart Drug Delivery Systems | |
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Session Chair(s)
 Ying ZHENG Professor, Institute of Chinese Medical Sciences  Ruibing WANG Associate Professor, Institute of Chinese Medical Sciences |
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16:30-16:50 |
 Guanghui MA Institute of Process Engineering, Chinese Academy of Sciences Talk title: Vaccine Delivery System |
16:50-17:10 |
 Wei WU Fudan University Talk title: Unraveling the Biological Fate of Drug Nanocarriers Based on Environment-Responsive Fluorophores |
17:10-17:30 |
 Can ZHANG China Pharmaceutical University Talk title: Living Cyto-pharmaceuticals for Tumor Immunotherapy |
17:30-17:50 |
 Xiaogang QU CAS Changchun Institute of Applied Chemistry Talk title: Recent Advances in Construction of Bio-inspired Nanozymes and Their Applications |
17:50-18:10 |
 Guangjun NIE National Center for Nanoscience and Technology Talk title: Development of Antitumor Vaccines based on Nanotechnology and Biotechnology |
| 18:10-18:25 |
Best Poster Awards & Closing Remarks
Delivered by Prof. Renhe Xu
Associate Dean (Research) of the Faculty of Health Sciences of the University of Macau
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